Ramipril 1.25 mg, 2.5 mg, 5 mg, 10 mg ေသြးတိုးက်ေဆး နွလံုးေဆး
treat high blood pressure ေသြးတိုးက်
angiotensin-converting enzyme (ACE) inhibitors.
reduce the risk of heart attack, stroke or death in people with a high risk
treat heart failure in people who have had a heart attack နွလံုး ေသြးေၾကာက်ဥ္းတာျဖစ္ျပီးတဲ့ နွလံု း မေကာင္းတဲ့ သူေတြမွာသံုး
relaxing the blood vessels in your body.
reduces stress on your heart and lowers your blood pressure.
You can take ramipril with or without food.
If you stop taking it suddenly: Don’t stop taking ramipril without talking to your doctor. Stopping this drug suddenly can cause your blood pressure to spike. This may increase your chance for a heart attack or stroke.
ဒံုးတိ ၾကီးျဖတ္ မရပါ ျဖတ္လို္က္ရင္ ေသြးေပါင္က ရုတ္ တရက္ ေစာင့္တက္နိုင္ပါတယ္ heart attack or stroke ျဖစ္ဖို့ အလား အလာမ်ားနိုင္
Ramipril oral capsule is used for long-term treatment. It comes with risks if you don't take it as prescribed. ေ၇၇ွည္
ေသာက္ရမယ့္ ေဆးျဖစ္တယ္
More common side effects
dizziness or faintness due to low blood pressure
cough
Cough warning ေခ်ာင္းဆိုးတတ္ ေဆးရပ္လိုက္ရင္ ေပ်ာက္သြား
Ramipril may cause a persistent cough. It will go away once you stop taking this medication.
dizziness
chest pain
nausea
vomiting
diarrhea
weakness or tiredness
ဆိုးက်ိ ုး ေျပာျပထားရမယ္ သိထား၇မယ္
low blood pressure. This is more common when you’re starting the drug or increasing doses. Symptoms include:
dizziness
lightheadedness ေသြး ေပါင္က် ေခါင္းမွ ု ေခါင္း တေ၇းေရးမွ ုျဖစ္လာနိုင္
allergic or hypersensitivity reaction (angioedema). Symptoms include: ဓါတ္ မတည့္တာေတြလညး္ ျဖစ္လာနိုင္
swelling of your face, lips, tongue, or throat
trouble breathing
stomach pain with or without nausea and vomiting
liver problems (jaundice). Symptoms include: အသည္း မေကာင္းတာေတြျဖစ္လာနုိင္
yellowing of your skin or the whites of your eyes အသား၀ါလာတာတို့ မ်က္လံုး ၀ါလာတာတို့
stomach pain ဗိုက္နာတာတို့
fatigue ေမာတာတို့
swelling (edema). Symptoms include: ေဖာ္လာတာတို့ ေၿခ လက္
swelling of your feet, legs, or hands
low white blood cell count. Symptoms include: ေသြး ျဖ ူဥ က်ဆင္းျပီး
sore throat လည္ေခ်ာင္း ေ၇ာင္တာတို့
fever ဖ်ားတာတုိ့
purple spot on your skin caused by internal bleeding (purpura) ကိုယ္ အတြင္း ေသြး ယို စိပ္ၿခင္း
fast or abnormal heart rate or palpitations. Symptoms include: နွလံုးခုန္ မမွန္ တာ
feeling like your heart is fluttering
high potassium levels. Symptoms include: kplus level မ်ားလာရင္
weakness အားယုတ္
arrhythmia (irregular heart rate) နွလံုး ခုန္ မမွန္
worse kidney function. Symptoms include: ေက်ာက္ကပ္ထိ
nausea and vomiting ပ်ိ ု ့အန္
decreased urine output when urinating ေသးထြက္နညး္
fatigue ေမာ
loss of appetite စားေသာက္ပ်က္
may increase your blood potassium when taken with ramipril. kplus နဲ့ တြဲေသာက္ရင္ Kplus levelမ်ားလာတတ္လို့ k plus level check ဖို့ လု့ိအပ္
Water pills (potassium-sparing diuretics) spironolactone န့ဲ တြဲ ေသာက္ရင္ Kplus level မ်ားလာနိုင္ k plus level check ဖို့ လု့ိအပ္
Mood stabilizer drugs lithium ေတြနဲံ့တြဲ ေသာက္ရင္ lithium level မ်ားတတ္
(NSAIDs), such as: အနာသက္သာေဆးေတြနဲ့ တြဲ ေသာက္ရင္ ramipril action က်ဆငး္ က်ိ ုးသက္ေရာက္မွ ုက်ဆငး္
naproxen
ibuprofen
diclofenac
a heart attack ျဖစ္ျပီး heart failure သမားေတြမွာ water pill ေတြ ဆီးေဆးေတြနဲ့ တြဲ ေသာက္၇င္
ေသြးေပါင္က်တတ္သည္ diuretics, such as:
hydrochlorothiazide
chlorthalidone
furosemide
bumetanide
metolazone
spironolactone
amiloride
triamterene
တြဲ မေပးရေသာ ေဆးမ်ား
aliskiren: Don’t take this drug with ramipril if you have diabetes or kidney problems.
angiotensin receptor blockers (ARBs), such as: တြဲ မေပးရ
losartan
valsartan
olmesartan
candesartan
telmisartan: This drug shouldn’t be used with ramipril.
angiotensin-converting enzyme (ACE) inhibitors, such as: တြဲ မေပးရ
benazepril
captopril
enalapril
lisinopril
Dosage for hypertension (high blood pressure) ေဆးေပးနညး္ မ်ား ကြဲ ျပားၿခင္း ေသြးတိုး အတြက္ဆုိရင္ တစ္မ် ိုးရိွ
Adult dosage (ages 18–64 years) ၁၈နွစ္နဲ့ ၆၄ နွစ္ၾကား
If you’re not taking a diuretic: 2.5–20 mg per day, taken by mouth in 1 or 2 divided doses per day. You may need to take 2 divided doses per day if the drug stops working before it’s time for your next dose.
ဆီးေဆး မေသာက္ရင္ 2.5–20 mg per day ၁ ေန့ ၁ ၾကိမ္ သို ့ ၂ ၾကိမ္
If you are taking a diuretic: The starting dose is 1.25 mg taken once per day.
ဆီးေဆး ေသာက္ေနရင္ 1.25 mg ၁ ေန့ တစ္ၾကိမ္
Child dosage (ages 0–17 years) ၁၇ နွစ္ ေအာက္ ကို မေလ့လာ၇ေသး
This medicine hasn’t been studied in children and shouldn’t be used in children younger than 18 years.
Senior dosage (ages 65 years and older) ၆၅ ေက်ာ္ရင္
As you age, your kidneys may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of this drug may stay in your body for a longer time. This increases your risk of side effects. Your doctor may start you on a lowered dose or a different schedule. This can help keep levels of this drug from building up too much in your body.
ေက်ာက္ကပ္ မေကင္း ဆိုးက်ိ ုးမ်ား ေဆး ေလွ ်ာ ့ ေပး ဖို့ လိုအပ္
Special considerations
Kidney problems: 1.25 mg once per day. Your doctor may increase your dose to 5 mg taken once per day if needed for blood pressure control.
ေက်ာက္ကပ္ သမားေတြကို 1.25 mg once per day ၁ ေန ့ ၁ ၾကိမ္ 5 mg taken once per day အထိ တိုး နို္္င္တယ္ ေသြးေပါင္ က်ဖို့ အတြက္
Renal artery stenosis or dehydration: The starting dose is 1.25 mg taken by mouth once per day. Your doctor may change your dose as needed.
နွလုး ံ ေလျဖတ္ တာေတြ ကို ေလွ ်ာ့က်ေ စဖို့ ေဆး ေပးနညး္
Dosage to reduce the risk of heart attack, stroke, or death
Adult dosage (ages 18–64 years)
2.5 mg taken by mouth once per day for 1 week.
Then 5 mg taken once per day for 3 weeks.
Your doctor will increase your dose as tolerated to 10 mg taken once per day. You may need to take 2 divided doses per day if your blood pressure is too high or if you’ve recently had a heart attack.
Child dosage (ages 0–17 years)
This medicine hasn’t been studied in children and shouldn’t be used in children younger than 18 years.
Senior dosage (ages 65 years and older)
As you age, your kidneys may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of this drug may stay in your body for a longer time. This increases your risk of side effects. Your doctor may start you on a lowered dose or a different schedule. This can help keep levels of this drug from building up too much in your body.
Special considerations
Renal artery stenosis or dehydration: The starting dose is 1.25 mg taken by mouth once per day. Your doctor may change your dose as needed.
Dosage for heart failure after a heart attack
Adult dosage (ages 18–64 years)
2.5 mg taken by mouth twice per day (total of 5 mg per day). If your blood pressure drops too low, you may need a lower dose of 1.25 mg taken twice per day. After one week, your doctor may increase your dose as tolerated up to 5 mg taken twice per day. Your doctor may continue to increase your dose once every 3 weeks if needed. The maximum dose is 20 mg.
Your doctor may watch you for at least 2 hours after you take the first dose to make sure that you can safely take this drug.
Child dosage (ages 0–17 years)
This medicine hasn’t been studied in children and shouldn’t be used in children younger than 18 years.
Senior dosage (ages 65 years and older)
As you age, your kidneys may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of this drug may stay in your body for a longer time. This increases your risk of side effects. Your doctor may start you on a lowered dose or a different schedule. This can help keep levels of this drug from building up too much in your body.
Special considerations
Kidney problems: 1.25 mg once per day. Your doctor may increase your dose up to 1.25 mg taken twice per day if needed. The maximum dose is 2.5 mg taken twice per day.
Renal artery stenosis or dehydration: The starting dose is 1.25 mg taken by mouth once per day. Your doctor may change your dose as needed.
Warnings
FDA warning: Use during pregnancy warning
This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to effects that may be dangerous.
You shouldn’t take this drug if you’re pregnant or plan to become pregnant. Ramipril may cause birth defects or be fatal to your unborn baby. Tell your doctor if you are planning to get pregnant or are pregnant.
ကိုယ္၀န္ ေဆာင္ သည္ မေပးရ ကေလး ေသတတ္
Allergic reactions warning
ဓါတ္ မတည့္သူမ်ား ေဖာ္ ေယာင္လာ တာ ေၿခ လက္ မေသာက္ရ
This drug may cause an allergic reaction. You may have swelling (angioedema) of your face, arms, legs, lips, tongue, windpipe, and stomach. Tell your doctor right away if you have swelling in these areas or have stomach pain. Don’t take any more ramipril until you talk to your doctor.
Low blood pressure warning
You may have low blood pressure especially during the first few days of treatment with this drug. You may feel lightheaded. Your risk for low blood pressure may be higher if you:
ေသြးေပါင္က်တတ္ လို့ ေခါငး္ အနညး္ငယ္မူးတတ္
ေသြး ေပါင္က်တာကို ဆိုးေစတဲ့ အခ်က္
eat a low salt diet ဆား နညး္နည္း စားၿခင္း
take a water pill (diuretic) ဆီးေဆးေသာက္ရင္ ေသြး ေပါင္က်တတ္
aren’t drinking enough fluids ေရေသာက္နညး္ရင္လညး္ ေသြး ေပါင္က်တတ္
are on dialysis
have diarrhea or are vomiting ၀မ္းေလွ် ာ အန္ရင္လညး္ ေသြး ေပါင္က်တတ္
Allergy warning
Ramipril can cause a severe allergic reaction. Symptoms include: ဓါတ္ မတည့္တာ ျဖစ္တတ္
trouble breathing အသက္ရွုရခက္တာတုိ့
swelling of your throat or tongue လွ ်ာ ေယာင္ လည္ေခ်ာင္း ေယာင္
hives အင္ျပင္ေတြထ
Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).
Warnings for people with certain health conditions ဓါတ္ မတည့္ ၇င္ မေသာက္နဲ့ ေသတတ္သည္
For people with kidney problems: People with kidney problems may have a higher risk for certain serious side effects from this drug, including high potassium levels. Tell your doctor if you have kidney problems, heart failure, and one- or two-sided renal artery stenosis. Your doctor will decide if ramipril is right for you. ေက်ာက္ကပ္ မေကာင္းတဲ့ လူေတြကို ေပးရင္ k plus levelမ်ားလာနိုင္
For people with liver problems: Ramipril should be used with caution if you have liver problems. This drug can worsen your liver function and change your electrolyte levels. အသည္း မေကာငး္ တဲ့ လူေတြကို ေပးရင္ အသည္း လုပ္ငန္း ေတြ ဆိုးလာနိုင္
For people with low white blood cells: Ramipril can cause low white blood cell counts. This can increase your risk of infections, especially if you have a history of lupus, kidney problems, or scleroderma. If you have any signs of an infection (such as a fever or sore throat), tell your doctor right away. ေသြး ျဖ ူ ဥ နညး္ေသာ ေရာဂါ ေတြမွာ မေပးရ
For people with diabetes: This drug can affect your blood sugar levels. Your doctor may need to change your dose of your diabetes drugs. Your doctor will tell you how often to test your blood sugar levels. ဆီး ခ် ို သမားေတြကို ေပးရင္ ေသြးထဲ သၾကားဓါတ္ က်တတ္လို့ တိုငး္တာ
ေနရမည္ သၾကားဓါတ္ကို
For children: This medicine hasn’t been studied in children and shouldn’t be used in children younger than 18 years.
Take as directed
If you don't take it at all: Ramipril reduces high blood pressure. If high blood pressure isn’t treated, it can lead to stroke, heart attack, heart failure, kidney failure, and vision problems.
လံုး၀ မေသာက္ရင္ ေသြး ေပါင္ မက် ဘူး ေသြးတိုးေနတတ္
If you don't take it on schedule: Your blood pressure may not improve or may get worse. You may have a higher chance of a heart attack or stroke. ပံုမွန္ မေသာက္၇င္ ေသြး ေပါင္းက မေကာင္းလာ နိုင္ ပို ဆိုးလာနိုင္ ေသြးေၾကာက်ဥ္း ဦးေနွာက္ ေသြး ေၾကာက်ဥ္းျပီးေလျဖတ္ တာေတြ ျဖစ္လာနိုင္
If you take too much: If you take too much ramipril, you could have dangerous levels of this drug in your body. You may have the following symptoms:
မ်ားမ်ား ေသာက္ပါက ေသြ းေပါင္က်ဆငး္
very low blood pressure
dizziness
kidney damage. Symptoms may include: ေက်ာက္ကပ္ထိ
nausea and vomiting
decreased urine output when urinating ေသးထြက္နညး္
fatigue ေမာ
loss of appetite စားေသာက္ပ်က္
Clinical monitoring
စစ္ေဆးမွ ုမ်ား ျပ ုလုပ္ေနရ
During treatment with this drug, your doctor will check the following to tell if this drug is working, is safe for you to take, and to check for side effects:
blood pressure ေသြး ေပါင္တုိင္းတဲ့ စက္ ၀ယ္ျပီးတိုငး္ ေသြး ေပါင္ က်တတ္လို့ ေဆး ဆိုးက် ိုးက က်ေန၇င္ ရပ္ထား ဆက္မေသာက္နဲ့
kidney function စစ္ ထိ ေက်ာက္ကပ္ပ်က္တတ္
liver problems ထိ တတ္ စစ္ရမယ္
electrolyte changes k+ မ်ားတတ္ ဆီးေဆးနဲ့ တြဲ ေပးရင္ နညး္တတ္သလို မ်ားတတ္လညး္ ၇ိွတတ္
blood counts ေသြးျဖ ူ ဥ နညး္တတ္ ကိုယ္ခံအားက် ျပီး ကူးစက္ေရာဂါ မိလြယ္တတ္
Ramipril, Oral Capsule
FDA warning: Use during pregnancy warning
- This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to effects that may be dangerous.
- You shouldn’t take this drug if you’re pregnant or plan to become pregnant. Ramipril may cause birth defects or be fatal to your unborn baby. Tell your doctor if you are planning to get pregnant or are pregnant.
- Ramipril oral capsule is available as both a generic and brand-name drug. Brand-name: Altace.
- This drug may cause sudden swelling of your face, arms, legs, lips, tongue, throat, and intestines. Stop taking ramipril and tell your doctor right away if you have swelling in these areas or have stomach pain.
- Ramipril is used to treat hypertension (high blood pressure). It’s also used to reduce the risk of heart attack, stroke, or death. It may also be given to treat heart failure in people who’ve had a heart attack.
Ramipril oral capsule is a prescription drug that’s available as the brand-name drug Altace. It’s also available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand.
Why it's used
Ramipril is used to:- treat high blood pressure
- reduce the risk of heart attack, stroke or death in people with a high risk
- treat heart failure in people who have had a heart attack
How it works
Ramipril belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. A class of drugs is a group of medications that work in a similar way. They are often used to treat similar conditions.Ramipril works by relaxing the blood vessels in your body. This reduces stress on your heart and lowers your blood pressure.
Ramipril oral capsule doesn’t cause drowsiness. However, it can cause other side effects.
More common side effects
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist. The more common side effects that occur with ramipril include:- dizziness or faintness due to low blood pressure
- cough
- dizziness
- chest pain
- nausea
- vomiting
- diarrhea
- weakness or tiredness
Serious side effects
Call your doctor right away if you have any of these serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:- low blood pressure. This is more common when you’re starting the drug or increasing doses. Symptoms include:
- dizziness
- lightheadedness
- allergic or hypersensitivity reaction (angioedema). Symptoms include:
- swelling of your face, lips, tongue, or throat
- trouble breathing
- stomach pain with or without nausea and vomiting
- liver problems (jaundice). Symptoms include:
- yellowing of your skin or the whites of your eyes
- stomach pain
- fatigue
- swelling (edema). Symptoms include:
- swelling of your feet, legs, or hands
- low white blood cell count. Symptoms include:
- sore throat
- fever
- purple spot on your skin caused by internal bleeding (purpura)
- fast or abnormal heart rate or palpitations. Symptoms include:
- feeling like your heart is fluttering
- high potassium levels. Symptoms include:
- weakness
- arrhythmia (irregular heart rate)
- worse kidney function. Symptoms include:
- nausea and vomiting
- decreased urine output when urinating
- fatigue
- loss of appetite
Ramipril oral capsule can interact with other medications, herbs, or vitamins you might be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins or herbs you are taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with Ramipril are listed below.
Potassium supplements
These supplements may increase your blood potassium when taken with ramipril. These supplements include:- potassium chloride
- potassium gluconate
- potassium bicarbonate
Water pills (potassium-sparing diuretics)
These medicines may increase your blood potassium when taken with ramipril. These drugs include:- spironolactone
- amiloride
- triamterene
Mood stabilizer drugs
Ramipril can increase the levels of lithium in your body. This means that you made have more side effects.Gold products
When taken with ramipril, certain joint pain rugs can cause side effects. These include reddening and warming of your face (flushing), nausea, vomiting, and low blood pressure. These drugs include:- injectable gold (sodium aurothiomalate)
Pain drugs
Certain pain drugs can decrease the effect of ramipril on your blood pressure. They can also cause kidney problems. These drugs include nonsteroidal anti-inflammatory drugs (NSAIDs), such as:- naproxen
- ibuprofen
- diclofenac
Water pills
When taken with ramipril, these medications can increase the risk of very low blood pressure in people with heart failure after a heart attack. These drugs include diuretics, such as:- hydrochlorothiazide
- chlorthalidone
- furosemide
- bumetanide
- metolazone
- spironolactone
- amiloride
- triamterene
Blood pressure drugs
When taken with ramipril, these blood pressure drugs can increase your risk of very low blood pressure, high blood potassium, and can affect how your kidneys function. These drugs include:- aliskiren: Don’t take this drug with ramipril if you have diabetes or kidney problems.
- angiotensin receptor blockers (ARBs), such as:
- losartan
- valsartan
- olmesartan
- candesartan
- telmisartan: This drug shouldn’t be used with ramipril.
- angiotensin-converting enzyme (ACE) inhibitors, such as:
- benazepril
- captopril
- enalapril
- lisinopril
Heart failure drugs
Do not take certain heart failure drugs called neprilysin inhibitors with ramipril. When taken with ramipril, these drugs increase your risk of angioedema (severe swelling of the skin). Examples of these drugs include:- sacubitril
This dosage information is for ramipril oral capsule. All possible dosages and forms may not be included here. Your doctor will tell you what dosage is right for you. Your dose, form, and how often you take it will depend on:
- your age
- the condition being treated
- how severe your condition is
- other medical conditions you have
- how you react to the first dose
Forms and strengths
Generic: ramipril- Form: Oral capsule
- Strengths: 1.25 mg, 2.5 mg, 5 mg, 10 mg
- Form: Oral capsule
- Strengths: 1.25 mg, 2.5 mg, 5 mg, 10 mg
Dosage for hypertension (high blood pressure)
Adult dosage (ages 18–64 years)- If you’re not taking a diuretic: 2.5–20 mg per day, taken by mouth in 1 or 2 divided doses per day. You may need to take 2 divided doses per day if the drug stops working before it’s time for your next dose.
- If you are taking a diuretic: The starting dose is 1.25 mg taken once per day.
This medicine hasn’t been studied in children and shouldn’t be used in children younger than 18 years.
Senior dosage (ages 65 years and older)
As you age, your kidneys may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of this drug may stay in your body for a longer time. This increases your risk of side effects. Your doctor may start you on a lowered dose or a different schedule. This can help keep levels of this drug from building up too much in your body.
Special considerations
Kidney problems: 1.25 mg once per day. Your doctor may increase your dose to 5 mg taken once per day if needed for blood pressure control.
Renal artery stenosis or dehydration: The starting dose is 1.25 mg taken by mouth once per day. Your doctor may change your dose as needed.
Dosage to reduce the risk of heart attack, stroke, or death
Adult dosage (ages 18–64 years)2.5 mg taken by mouth once per day for 1 week. Then 5 mg taken once per day for 3 weeks. Your doctor will increase your dose as tolerated to 10 mg taken once per day. You may need to take 2 divided doses per day if your blood pressure is too high or if you’ve recently had a heart attack.
Child dosage (ages 0–17 years)
This medicine hasn’t been studied in children and shouldn’t be used in children younger than 18 years.
Senior dosage (ages 65 years and older)
As you age, your kidneys may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of this drug may stay in your body for a longer time. This increases your risk of side effects. Your doctor may start you on a lowered dose or a different schedule. This can help keep levels of this drug from building up too much in your body.
Special considerations
Renal artery stenosis or dehydration: The starting dose is 1.25 mg taken by mouth once per day. Your doctor may change your dose as needed.
Dosage for heart failure after a heart attack
Adult dosage (ages 18–64 years)- 2.5 mg taken by mouth twice per day (total of 5 mg per day). If your blood pressure drops too low, you may need a lower dose of 1.25 mg taken twice per day. After one week, your doctor may increase your dose as tolerated up to 5 mg taken twice per day. Your doctor may continue to increase your dose once every 3 weeks if needed. The maximum dose is 20 mg.
- Your doctor may watch you for at least 2 hours after you take the first dose to make sure that you can safely take this drug.
This medicine hasn’t been studied in children and shouldn’t be used in children younger than 18 years.
Senior dosage (ages 65 years and older)
As you age, your kidneys may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of this drug may stay in your body for a longer time. This increases your risk of side effects. Your doctor may start you on a lowered dose or a different schedule. This can help keep levels of this drug from building up too much in your body.
Special considerations
Kidney problems: 1.25 mg once per day. Your doctor may increase your dose up to 1.25 mg taken twice per day if needed. The maximum dose is 2.5 mg taken twice per day.
Renal artery stenosis or dehydration: The starting dose is 1.25 mg taken by mouth once per day. Your doctor may change your dose as needed.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.
FDA warning: Use during pregnancy warning
- This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to effects that may be dangerous.
- You shouldn’t take this drug if you’re pregnant or plan to become pregnant. Ramipril may cause birth defects or be fatal to your unborn baby. Tell your doctor if you are planning to get pregnant or are pregnant.
Allergic reactions warning
This drug may cause an allergic reaction. You may have swelling (angioedema) of your face, arms, legs, lips, tongue, windpipe, and stomach. Tell your doctor right away if you have swelling in these areas or have stomach pain. Don’t take any more ramipril until you talk to your doctor.Low blood pressure warning
You may have low blood pressure especially during the first few days of treatment with this drug. You may feel lightheaded. Your risk for low blood pressure may be higher if you:- eat a low salt diet
- take a water pill (diuretic)
- aren’t drinking enough fluids
- are on dialysis
- have diarrhea or are vomiting
Cough warning
Ramipril may cause a persistent cough. It will go away once you stop taking this medication.Allergy warning
Ramipril can cause a severe allergic reaction. Symptoms include:- trouble breathing
- swelling of your throat or tongue
- hives
Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).
Warnings for people with certain health conditions
For people with kidney problems: People with kidney problems may have a higher risk for certain serious side effects from this drug, including high potassium levels. Tell your doctor if you have kidney problems, heart failure, and one- or two-sided renal artery stenosis. Your doctor will decide if ramipril is right for you.For people with liver problems: Ramipril should be used with caution if you have liver problems. This drug can worsen your liver function and change your electrolyte levels.
For people with low white blood cells: Ramipril can cause low white blood cell counts. This can increase your risk of infections, especially if you have a history of lupus, kidney problems, or scleroderma. If you have any signs of an infection (such as a fever or sore throat), tell your doctor right away.
For people with diabetes: This drug can affect your blood sugar levels. Your doctor may need to change your dose of your diabetes drugs. Your doctor will tell you how often to test your blood sugar levels.
Warnings for other groups
For pregnant women: Ramipril is a category D pregnancy drug. That means two things:- Research in humans has shown adverse effects to the fetus when the mother takes the drug.
- This drug should only be used during pregnancy in serious cases where it's needed to treat a dangerous condition in the mother.
For women who are breastfeeding: Ramipril may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your baby. You may need to decide whether to stop breastfeeding or stop taking this medication.
For seniors: Older adults may process drugs more slowly. A normal adult dose may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dose or a different schedule.
For children: This medicine hasn’t been studied in children and shouldn’t be used in children younger than 18 years.
Ramipril oral capsule is used for long-term treatment. It comes with risks if you don't take it as prescribed.
If you don't take it at all: Ramipril reduces high blood pressure. If high blood pressure isn’t treated, it can lead to stroke, heart attack, heart failure, kidney failure, and vision problems.
If you stop taking it suddenly: Don’t stop taking ramipril without talking to your doctor. Stopping this drug suddenly can cause your blood pressure to spike. This may increase your chance for a heart attack or stroke.
If you don't take it on schedule: Your blood pressure may not improve or may get worse. You may have a higher chance of a heart attack or stroke.
What to do if you miss a dose: If you forget to take your dose, take it as soon as you remember. If it’s just a few hours before the time for your next dose, then wait and only take one dose at that time. Never try to catch up by taking two doses at once. This could cause toxic side effects.
If you take too much: If you take too much ramipril, you could have dangerous levels of this drug in your body. You may have the following symptoms:
- very low blood pressure
- dizziness
- kidney damage. Symptoms may include:
- nausea and vomiting
- decreased urine output when urinating
- fatigue
- loss of appetite
How to tell this drug is working: You can tell if ramipril is working because your blood pressure will be lower.
Keep these considerations in mind if your doctor prescribes Ramipril oral capsule for you.
General
You can take ramipril with or without food.Ramipril capsules should be swallowed whole.
Storage
- Keep it from 59°F to 86°F (15°C to 30°C).
- Don’t freeze this drug.
- Keep it away from light.
- Keep it away from high temperature.
- Don’t store this medication in moist or damp areas, such as bathrooms.
Refills
A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.Travel
When traveling with your medication:- Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
- Don’t worry about airport X-ray machines. They can’t hurt your medication.
- You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
- Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.
Self-management
You may need to check your blood pressure at home. You’ll need to purchase a blood pressure monitor to do this.You should keep a log with the date, time of day, and your blood pressure readings. Bring this diary with you to your doctor appointments.
Your doctor will tell you what to do if your blood pressure is too high or low. Based on your blood pressure readings, your doctor may change your medication.
Clinical monitoring
During treatment with this drug, your doctor will check the following to tell if this drug is working, is safe for you to take, and to check for side effects:- blood pressure
- kidney function
- liver problems
- electrolyte changes
- blood counts
Hidden costs
If your doctor asks you to check your blood pressure at home, you’ll need to buy a blood pressure monitor. These are available at most pharmacies.Insurance
Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other options that may work for you.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
1. About ramipril
Ramipril is a medicine widely used to treat high blood pressure and heart failure. It's also prescribed after a heart attack.
Ramipril helps prevent future strokes, heart attacks and kidney problems. It also improves your survival if you're taking it for heart failure or after a heart attack.
This medicine is available on prescription. It comes as tablets, capsules and as a liquid that you swallow.
Ramipril helps prevent future strokes, heart attacks and kidney problems. It also improves your survival if you're taking it for heart failure or after a heart attack.
This medicine is available on prescription. It comes as tablets, capsules and as a liquid that you swallow.
Uses
Ramipril is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Ramipril is also used to improve survival after a heart attack. It may also be used in high risk patients (such as patients with heart disease/diabetes) to help prevent heart attacks and strokes. This medication may also be used to treat heart failure in patients who have had a recent heart attack.Ramipril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily.
How to use Ramipril
Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily.If you are taking the capsule form of ramipril, swallow it whole. If you have difficulty swallowing the capsule, the capsule may be opened and the contents sprinkled onto cool applesauce (about 4 ounces) or mixed in half a glass of water or apple juice (4 ounces/120 milliliters). Swallow or drink the whole mixture.
The dosage is based on your medical condition and response to treatment.
To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.
Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
For the treatment of high blood pressure, it may take several weeks before you get the full benefit of this medication. Tell your doctor if your condition does not improve or if it worsens (such as your blood pressure readings remain high or increase).
Side Effects
Dizziness, lightheadedness, or tiredness may occur as your body adjusts to the medication. Dry cough may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these unlikely but serious side effects occur: fainting, symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat).
Although ramipril may be used to prevent kidney problems or treat people who have kidney problems, it may also rarely cause serious kidney problems or make them worse. Your doctor will check your kidney function while you are taking ramipril. Tell your doctor right away if you have any signs of kidney problems such as a change in the amount of urine.
This drug may rarely cause serious (possibly fatal) liver problems. Tell your doctor right away if you notice any of the following rare but serious side effects: yellowing eyes/skin, dark urine, severe stomach/abdominal pain, persistent nausea/vomiting.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Precautions
Before taking ramipril, tell your doctor or pharmacist if you are allergic to it; or to other ACE inhibitors (such as benazepril); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: history of an allergic reaction which included swelling of the face/lips/tongue/throat (angioedema), blood filtering procedures (such as LDL apheresis, dialysis), high level of potassium in the blood.
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Too much sweating, diarrhea, or vomiting may cause loss of too much body water (dehydration) and increase your risk of lightheadedness. Report prolonged diarrhea or vomiting to your doctor. Be sure to drink enough fluids to prevent dehydration unless your doctor directs you otherwise.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
This product may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist.
Older adults may be more sensitive to the side effects of this drug, including dizziness and increases in potassium level.
This medication is not recommended for use during pregnancy. It may harm an unborn baby. Consult your doctor for more details. (See also Warning section.)
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Interactions
See also Precautions section.Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug include: aliskiren, certain drugs that weaken the immune system/increase the risk of infection (such as everolimus, sirolimus), lithium, drugs that may increase the level of potassium in the blood (such as ARBs including losartan/valsartan, birth control pills containing drospirenone), sacubitril, telmisartan.
Some products have ingredients that could raise your blood pressure or worsen your heart failure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).
A very serious reaction may occur if you are getting injections for bee/wasp sting allergy (desensitization) and are also taking ramipril. Make sure all your doctors know which medicines you are using.
Overdose
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting.Notes
Do not share this medication with others.Lifestyle changes such as stress reduction programs, exercise and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.
Laboratory and/or medical tests (such as kidney function, potassium levels) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
Check your blood pressure regularly while taking this medication. Learn how to monitor your own blood pressure at home, and share the results with your doctor.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Do not double the dose to catch up.Storage
Store at room temperature away from light and moisture. If you are taking the capsule form of ramipril and have opened the capsule and mixed the contents with food or liquid, then the mixture can be kept at room temperature for up to 24 hours or refrigerated for up to 48 hours. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised May 2017. Copyright(c) 2017 First Databank, Inc.
https://en.wikipedia.org/wiki/Ramipril
https://www.webmd.com/drugs/2/drug-8843/ramipril-oral/details
https://www.nhs.uk/medicines/ramipril/
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